2-Methyl-AP-237 (other names: 2-methyl Buccinazine, 2-MAP) is an opioid drug, an active opioid receptor agonist, a methylated analog of AP-237(Bucinnazine) with similar structure and effects. The drug AP-237(Bucinnazine) has been actively used to treat pain in cancer patients.
History
This substance is a designer drug for scientific and chemical research and first began to be sold online in 2019.
Chemistry
2-Methyl-AP-237 is a methylated analog of AP-237(Bucinnazine).
Pharmacology
2-Methyl-AP-237 is a designer substance whose toxicological and pharmacological properties are not fully understood. All data presented are from observational and chemical studies in mice.
This substance is an agonist of mu-opioid receptors and activates them. 2-Methyl-AP-237 is approximately 4 times more potent than morphine.
This drug may cause opioid dependence if abused and used frequently.
Legal status
This drug has an unclear legal status and can be sold as a research substance for scientific purposes and tests in specially equipped laboratories in the EU and other countries.
Product Name: 2-Methyl-AP-237
Other Name(s): 2-methyl Buccinazine, 2-MAP
IUPAC Name: 1-[2-methyl-
CAS: 98608-59-4, 98608-61-8
Molar Mass: 322.9 g/mol
Molecular Formula: C18H26N2O • HCl
InChi Code: InChI=1S/C18H26N2O.ClH/c1-3-8-18(21)20-14-13-19(15-16(20)2)12-7-11-17-9-5-4-6-10-17;/h4-7,9-11,16H,3,8,12-15H2,1-2H3;1H/b11-7+;
InChIKey: GPYVJSNBBPAWLD-RVDQCCQOSA-N
Canonical SMILES: CC(NCC)CC1=C(F)C=CC=C1.Cl
Formulation: A crystalline solid

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