Nortilidine is an opioid analgesic derivative of tilidine, which has an opioid activity equivalent to morphine. This drug has antagonistic activity on NMDA, due to the (1R,2S) isomer, and also acts as a dopamine reuptake inhibitor.
Chemistry
Nortilidine is a metabolite of tilidine and has a related structure.
Pharmacology
Studies in mice have shown that Nortilidine acts as an analgesic, causing a relaxing effect. This preparation is a research product and its pharmacological and toxicological properties are under study.
This drug has never been used in medicine or tested on humans, Nortilidine is a designer drug and needs to be investigated in a laboratory.
Legal status
Nortilidine may not be banned in many countries as a research substance. In countries where tilidin analogues are controlled by law, it may not be legal.
Technical Information:
Product Name: Nortilidine
Synonyms: Nortilidine HCL
CAS: 38677-94-0
IUPAC: ethyl (1R,2S)-2-(methylamino)-1-phenylcyclohex-3-ene-1-carboxylate
Molecular Formula: C16H21NO2
Molecular Weight: 259.34 g/mol
Purity: 98.0 % min.
Formulations: A crystalline solid
Solubility:
- DMSO: Soluble
- Methanol: Soluble
SMILES: CCOC(=O)[C@]1(CCC=C[C@@H]1NC)C2=CC=CC=C2
Stability: ≥ 4 years

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